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Time to first occurrence of new-onset DM was assessed according to randomised treatment with dapagliflozin or placebo over median 11.6 months

Myokines produced by skeletal muscle, such as interleukin-6 (IL-6) and irisin, play a key role in mediating these immune and metabolic responses through autocrine, paracrine, and endocrine effects

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Biomed ., 15 (4), 203208