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This suggests that astrocytes can modulate synaptic receptivity by mediating signaling and dendritic localization of neurexins

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The propensity score was constructed from age at the index date (continuous), sex, race, region, number of RMS relapses in the preindex period (0, 1, 2+), prior DMT in the preindex period, RMS disability in the preindex period, Deyo-Charlson comorbidity index (DCCI) in the preindex period (continuous), and Psychiatric Diagnosis Group index in the preindex period (continuous)

The decreased abundance of SCFA-producing bacteria in the gut caused by antibiotic administration has also been associated with enhancing pathogenic colonisation, including by the fungal species Candida albicans known to modulate the permeability and integrity of the gut barrier during infection (Allert et al