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The authors note that further research is needed to better understand these effects and to inform clinical guidelines as use of GLP-1 medications continues to expand in patients seeking body contouring procedures

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The mechanism linking GHK-Cu copper delivery to AMPK activation may involve mitochondrial copper incorporation into Complex IV (cytochrome c oxidase

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Likely not a fit: Patients with significant obesity or a metabolic condition will need the full-dose efficacy of standard GLP-1 regimens