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Allergies: A known allergy to semaglutide or any of its components is a contraindication

An August 2024 study published in JAMA Network Open showed the odds for suicidal ideation were higher in individuals who took semaglutide compared with other weight-loss medications for type 2 diabetes

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For example, OTUs that were decreased in both groups in visit 3 that attained statistical significance included the families Coriobacteriaceae , Peptostreptococcaceae , Lachnospiraceae , and Ruminococcaceae , which all returned to levels similar to baseline in the last two time points after the cessation of the antimicrobial, as depicted in Fig