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No severe TEAEs or serious TEAEs were observed in either study
8 , e70490 (2025)
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When AhR was bound to its agonist, AHR was dissociated from the protein complex and translocated to the nucleus, where it interacted with aryl hydrocarbon receptor nuclear transporter (ARNT) to form a dimer, and activated transcription of target genes by binding to specific enhancer sequences in the regulatory regions of target genes, such as the aryl hydrocarbon receptor response element on the cytochrome P450 Family 1 subfamily B member 1 (CYP1B1) promoter (78)
M.SalvatoriR.AssiratiJ
For years, the name reduced a complex, longterm endocrine disorder to a misunderstanding about cysts with an overemphasis on the ovaries, leading to missed diagnoses and inadequate care
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