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Phase 2 trial results showing up to 24.2% body weight loss the highest ever recorded for a pharmaceutical intervention have positioned retatrutide as a possible next-generation treatment that could surpass even tirzepatide and semaglutide

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Qsymia is a once-daily oral capsule combining two older medications phentermine, a stimulant appetite suppressant, and topiramate, an anticonvulsant while Zepbound is a once-weekly injection containing tirzepatide, a dual GLP-1 and GIP hormone agonist that works with your body's natural hunger and metabolism signals