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As a key bone transcription factor, RUNX2 plays an important role in the initiation of osteogenic differentiation and bone formation (Park et al., 2019)

doi: 10.1016/j.cardfail.2021.01.022

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Fundam Clin Pharmacol 2007

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The Breakthrough Foundation says the prizes were created to "celebrate the wonders of our scientific age." Another Canadian, Maaike van Kooten of National Research Council Canada, shared a $100,000 US prize called New Horizons in Physics with two international colleagues for work in optics to view exoplanets