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Reduction in depression, cognitive decline and dementia in older people

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Thus, the risk factor for groups such as older adults and people with diabetes, hypertension, and cardiovascular diseases is understood, as these individuals already have a state of oxidative stress (Liguori et al

4c, replacement of the first six residues of GLP-2 by those of GLP-1 (i.e., double mutant D 3P E and S 5P T) decreased cAMP accumulation by 12-fold compared to the native peptide, suggesting that subtle substitution may directly alter receptor activation

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