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The primary endpoint was a change in A1C

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Minor criteria are (1) foot deformities including broad/plump forefoot, brachydactyly with excessive skin, pes planus, hallux valgus, and piezogenic papules

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doi: 10.1152/physiolgenomics.00029.2016 32 PechlivanovaDPetrovKGrozdanovPNenchovskaZTchekalarovaJStoynevA