with previous use of GLP-1 RAs exhibiting an SMD of 0.835
Complications of Carnitine Deficiency Syndrome include organ damage to the liver, heart, brain, and various skeletal muscles of the body, including heart muscle weakness (cardiomyopathy) Brain injury may present severe brain dysfunction (encephalopathy), irreversible learning problems, and mental retardation Another complication includes problems with the metabolism of the body, especially relating to fat and energy metabolism
These metabolic abnormalities are involved in hypoalbuminemia and hyperammonemia, which induce several complications of LC, including hepatic encephalopathy, sarcopenia, and muscle cramps (Figure 1)
On the other hand, semaglutide is a GLP-1 agonist (glucagon-like peptide-1) only, which mimics the effects of the GLP-1 hormone in the body
Omega-3 fatty acids, mainly from fish oil, are frequently used due to their role in brain development and inflammation reduction