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The melanocortin system: POMC and endogenous ligands All endogenous melanocortin ligands derive from a single precursor, proopiomelanocortin (POMC) , a 241-amino acid polypeptide encoded by the POMC gene on chromosome 2p23.3

Adults with obesity were more likely to achieve a 10% or greater weight loss at 1 year if they continued using their prescribed obesity medication, according to findings published in Obesity

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