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Collectively, these findings indicated that P-Mn/TI@mHSA not only suppressed inflammatory cytokine expression but also serve as an effective regulator in promoting the phenotypic transition of macrophages from M1 to M2

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or preparation, review, approval of the manuscript or decision to submit the manuscript for publication REF, JS and LD had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis

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Additionally, in a high-fat diet-induced hypertension mouse model, valproic acid was found to inhibit HDAC1, reducing angiotensin II and its receptor expression, thereby preventing hypertension progression [79]

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