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Favorable Safety Profile AOD-9604 demonstrated a safety profile indistinguishable from placebo across over 900 human participants

This allows the body to access vitamins and minerals immediately without relying on digestion

Peripheral tissues like skin (high turnover rates, moderate mitochondrial capacity) are particularly vulnerable

Oxidation of either methionine 351 or methionine 358 in alpha-1 antitrypsin causes loss of anti-neutrophil elastase activity

Therapeutic targeting of immune-inhibitory and stimulatory pathways can alter the immune systems tolerance for self, resulting in damage to normal cells, known as immune-related adverse events (irAEs)