Glyoxalase I (EC 4.4.1.5) catalyzes the conversion of methylglyoxal and reduced glutathione to S -D-lactoylglutathione
Research confirms that vitamin C helps restore glutathione to its reduced, active form
Disease and aging can both detract from bone marrow stem cell reservoirs and affect immune function in ways that can directly cause miscarriage
Free radicals are unstable molecules that damage cell membranes, proteins, and DNA, and antioxidants like glutathione are how the body keeps that damage in check
Animals were housed and bred in a pathogen-free animal facility at the Keck School of Medicine, University of Southern California (USC), in accordance with protocols approved by the Institutional Animal Care and Use Committee
via ferritinophagy (Sun et al., 2023)