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In the past, theyve been prescribed primarily to treat people with type 2 diabetes, but theyre now being used by a wider range of people for general weight loss, but also migraine and hormone management in some cases
The Microdose GLP-1 Protocol ($129/month flat) begins at 0.10.25mg weekly, allowing adaptation before reaching therapeutic doses
Specific safety considerations under investigation include the long-term effects of sustained glucagon receptor activation
Compounded semaglutide vials can generally stay unrefrigerated for shorter time, but it depends on the specific formulation and the preservatives used
For instance, a 10 mg/kg dose significantly reduced body weight by 11.2% and 7.4% in DIO mice and rats, respectively