44,45 Using the FDA Sentinel System, Maro et al found that the incidence of NAION was not increased within 6 months of semaglutide initiation
Corbin KD, Carnero EA, Allerton TD et al (2023) Glucagon-like peptide-1/glucagon receptor agonism associates with reduced metabolic adaptation and higher oxidation: a randomized trial
The Benefits Unveiled: How Hormone Replacement Therapy Could Help Your Overall Health Properly balanced hormones support your entire body: Physical improvements: Reduced hot flashes and night sweats Better sleep quality and energy levels Maintained bone density, lowering osteoporosis risk Healthier skin and hair Mental wellness: Improved mood stability Sharper mental clarity Reduced anxiety and irritability Long-term health: Support for cardiovascular health when started appropriately Better weight management Enhanced sexual function and intimacy The North American Menopause Society supports hormone therapy for symptomatic women when health risks are evaluated and regular screenings are maintained
Even with careful balancing, there can still be confounding
Newer options like retatrutide show even more promise in clinical trials
Tirzepatide-Induced Gastrointestinal Manifestations: A Systematic Review and Meta-Analysis