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Clinical trials show that weight loss plateaus around 1.0 to 2.0 mg for many patients, meaning higher doses may not produce additional significant weight loss

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81830109, 82204819, 82274173), the Shanghai Municipal Health Commission (grant no

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However, due to poor metabolic stability of angiotensin IV and many AnglV analogues, the inability of early analogues to penetrate the blood brain baixier, and the failure to identify the AT4 receptor, no pharmaceutical company has moved forward with their development