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Specifically, CRISPR-based approaches have identified CSC dependencies on metabolic pathways, survival factors, and immune evasion mechanisms, providing new opportunities for CSC-directed therapies

Critical role of AMPK in redox regulation under glucose starvation

Oxidative modification of NK surface receptors NKG2D and NKp46 reduces their ability to recognise and bind infected target cells

Inhibition of TLR4 or TRIF expression protects mice from H5N1-induced ALI 80

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