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Based on the impact of PfK13 mutations on hemoglobin uptake and GSH levels in the parasite, one can hypothesise that a decrease in redox-active ferrous heme in artemisinin resistant parasites leads to elevated GSH within the cell, potentially making them more tolerant to artemisinin-induced oxidative stress

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Description AOD9604 (Metabolic Research Peptide) AOD9604 is a synthetic peptide analogue derived from the C-terminal region of human growth hormone (specifically residues 177-191), modified with an additional tyrosine residue at the N-terminus