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The variation reflects differences in pharmacy overhead, testing protocols, ingredient sourcing, and profit margins

Zepbound is approved by the FDA as a weight loss management treatment for people with obesity or those who are overweight with at least one weight-related condition such as high blood pressure

No difference from baseline was seen at 20 and 26 weeks

Cheaper, compounded GLP-1s, often sold by online providers including, in addition to Hims & Hers, Ro, Eden and Weight Watchers, are legal and contain the same active ingredients as their pricier counterparts

However, it may also cause more gastrointestinal side effects compared to semaglutide, making individual tolerance an important factor when choosing between the two