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However, the direct vascular protective effects of GLP-1 RAs, including anti-inflammatory and endothelial actions, could theoretically operate independently of baseline metabolic status [31]

Denu RA, Hematti P

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GLP-1 agonists generally produce a stronger reduction in blood sugar and body weight than metformin alone, though metformin remains highly effective as a foundation therapy

Transmission Electron Microscopy(TEM) Cell pellets were collected by centrifugation and immediately fixed in electron microscopy fixative at 4 C for 24 h