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10.1155/2014/360438 Oxidative Med Cell Longevity

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However, these regimens have shortcomings like medication associated issues (susceptibility to infections, liver problems, bone density loss, and allergic reactions), limited efficacy (frequent flare-ups), biologic therapy risks (infusion reactions, may reduce the effectiveness of antibodies), surgery considerations (may cause potential complications), cost and accessibility (biologics and JAK inhibitors), psychological impact etc

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Several proteins, involving covalent or non-covalent cysteine modifications have been also identified

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