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Advice for Healthcare Professionals The MHRA has advised that healthcare professionals remain vigilant for symptoms of acute pancreatitis, which may be challenging to recognise in early stages, and use GLP-1/GIP receptor agonists and GLP-1RAs with caution in patients with a history of pancreatitis
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10 Diabetic retinopathy (DR), occurred in 22% of diabetes patients and 6% suffer from vision threatening DR which might lead to irreversible vision impairment even blindness
doi: 10.1016/j.molcel.2022.01.008 43 KantariCWalczakH
GIP receptor activation may contribute to improved metabolic function, while GLP-1 receptor agonism primarily mediates appetite suppression through central nervous system pathways affecting satiety centers in the hypothalamus
