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Implications for employers: This research suggests that those who are treated effectively with GLP-1 medications for obesity will need to remain on these for the long term

The consistency of A1C reduction across these diverse trials, regardless of background therapy or patient characteristics, establishes tirzepatide as one of the most effective glucose-lowering medications currently available

Retatrutide will need to demonstrate differentiated value, whether through superior efficacy, unique hepatic effects, or other clinical advantages, to carve out a distinct market position

They may reduce your appetite, so smaller portions may feel better, but you can still eat balanced, nutrient-dense meals that support your health and energy needs

doi: 10.1016/j.abb.2018.02.011