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Scheggi et al., 2016), microglia activation, and stress-induced apoptosis (Rinwa and Kumar 2013

Resveratrol: A powerful polyphenol that activates longevity proteins (sirtuins)

Mitochondrial GSTs are known as the kappa class in mammals and are mostly found in the mitochondrial matrix [60] and peroxisomes [61]

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However, in all cases, sustained UPR activation promotes neurodegeneration by exacerbating ER stress, initiating apoptotic pathways, and impairing cellular recovery mechanisms