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how mitochondrial-derived signals (e.g., specific lipids, peptides, or ROS subsets) propagate to regulate cytoplasmic iron metabolism, lipid peroxidation, or antioxidant systems remains elusive

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Baek, R

In Vitro Research (Cell Culture Models): Glutathione is frequently introduced into cell culture systems to evaluate oxidative stress responses, redox balance, and cellular viability

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Beyond its crucial role as a primary glutathione precursor, NAC possesses its own potent, direct antioxidant capabilities that function independently of the glutathione pathway