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The inhibition of YAP substantially reduces leukocyte, macrophage, and neutrophil infiltration following pressure overload, suggesting that YAP contributes to heart failure by promoting cardiomyocyte dedifferentiation and inflammatory responses in diabetic hearts under stress[200]

Cancer Discov 8(2):164-173, 2018

Diabetes: Blood sugar imbalances can cause fatigue

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If you ingest more of this nutrient than your body requires, the excess amount should be excreted in your urine