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These patients represent a very small proportion of the population (approximately 1 of 200,000 individuals in the world) and have very severe hyperhomocysteinemia that can reach 400 mol/L

Results: Cumulative survival rates were 87.1% at 1 year, 63.7% at 3 years, and 41.2% at 5 years

However, if the condition persists or is related to other factors, medical evaluation and treatment may be necessary

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doi: 10.1158/0008-5472.Can-08-1321 96 ZhaoHLiJLiXHanCZhangYZhengLet al