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split doses for steady levels during active recovery phases)

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A accumulation induces excessive free radical generation, which activates Drp1 and its cofactor Fis1, resulting in impaired mitochondrial trafficking to synapses and significantly reduced synaptic ATP production

497 Although the inhibitor of NMN synthase NAMPT reduces NAD + level, it can still provide strong morphological and functional protection for damaged synapses and axons

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Allosteric modulation of Class C GPCRs: a novel approach for the treatment of CNS disorders