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These compounds do not replace BDNF

In sciatic nerve injury models, treated animals showed faster functional recovery and reduced axonal degeneration

The common protein must be taken in by macrophages or dendritic cells to start the process, causing an antigen presentation on MHC II molecules

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For example, researchers from a 2016 review of data on the gut-brain axis and BPC-157 explain that the peptide could maintain gastrointestinal mucosa, modulate serotonergic and dopaminergic systems, regenerate peripheral nerves, protect certain neurons, counteract various types of lesions, promote wound healing, and more.7 Some of these possible benefits are due to BPC-157s promotion of the cell migration of vascular endothelial cells.24 This means that the peptide can encourage the formation of new blood vessels (also known as angiogenesis)