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[] In an in vivo study using male Wistar rats, Saxena et al .(2005) [] demonstrated that treatment using DMSA and its two analogues, MmDMSA and MchDMSA, resulted in considerable improvement to serum biochemical variables and led to reduced brain DNA damage

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10.1038/nature20814 Nature 181 QiangW.YauW.-M.LuoY.MattsonM

When this happens, the gradual buildup of dysfunctional mitochondria can lead to increased inflammation, which is associated with a higher risk of chronic diseases, like cancer or dementia.8 15 So, if urolithin A can kickstart mitophagy, then it may lower your risk for chronic disease, increasing your healthspan and your lifespan

This means ensuring the researchers who use them have the foundational knowledge to design effective studies