Effect of dulaglutide versus liraglutide on glucose variability, oxidative stress, and endothelial function in type 2 diabetes: a prospective study
Weight loss drugs and muscle loss: a growing concern The introductions of semaglutide (Ozempic, Wegovy) and tirzepatide (Zepbound, Mounjaro) have revolutionized healthcare, but physicians are finding that patients often lose a significant portion of their lean muscle mass while on the medications
PMCID: PMC8503559
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Research on skeletal muscle biopsies from DMD patients has revealed decreased NAD + levels, increased PARP activity 253 and dysfunction of mitochondrial metabolism 254,266
Because tirzepatide can be powerful even at lower doses for some patients, careful provider oversight is still important