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Metformin-inclusive sulfonylurea therapy reduces the risk of parkinsons disease occurring with type 2 diabetes in a Taiwanese population cohort
Vanhee C, et al
This was the case in our pre-registered primary analysis (where we report a significant group effect across groups of participants with type-2 diabetes, on and off semaglutide, and BMI-matched and -unmatched healthy controls, which numerically show decreasing acceptance bias), and in our exploratory dimensional finding that increasing risk of diabetes is associated with lower acceptance bias across study groups
Importantly, this study also highlights the importance of determining the functional impact of muscle loss and whether that is reflected in a loss of strength as well. Kais Rona, MD Its extremely important to continue to study the potential side effects, including the loss of lean muscle mass, associated with GLP-1 medications as it can have major effects on our healthcare system as a whole, Rona added
The results of this systematic review and meta-analysis demonstrate that glucagon-like peptide-1 receptor agonists (GLP-1RAs) reduce the risk of major adverse cardiovascular events (MACE)
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