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The roles of GSTT1 polymorphism in TCC and GSTP1 polymorphisms in both cancers are still controversial

Additional testing may be considered for people with a family history of premature heart disease, metabolic risk, abnormal cholesterol results, known cardiovascular disease, or uncertainty after standard testing: ApoB, Lp(a), and hs-CRP may help reveal particle burden, inherited risk, and inflammation that are not fully captured by LDL cholesterol alone

21 Another small open trial with 37 participants also found this combination reduced IC/BPS symptom severity after six months

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