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NIS Labs

Short-chain fatty acids (SCFAs) produced by the microbiota can promote intestinal barrier repair through a variety of mechanisms, including activating inflammasomes and affecting the secretion of interleukin (IL)-18, promoting epithelial cell migration, regulating tight junction protein expression, activating G protein-coupled receptors, and inhibiting tissue protein deacetylases [10, 11]

Studies using cultured tendon cells and animal models have shown that BPC-157 may promote cell survival under stress conditions and enhance the migration and spreading of fibroblasts, which are important for tissue structure and repair

10.1016/j.bpobgyn.2018 24

446 Astrocytes are fundamental for both excitatory and inhibitory transmission through glutamate glutamate (GABA)-glutamine shuttle 447 and chloride ionostasis 330 and are thus well positioned to contribute to OCD pathophysiology