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Zepbound is indicated for chronic weight management and treatment of moderate to severe obstructive sleep apnea (OSA) in patients with obesity or overweight with at least one weight-related condition when combined with a healthy lifestyle and dietary modifications

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It is both a GLP-1 (glucagon-like peptide-1) receptor agonist and a GIP (glucose-dependent insulinotropic polypeptide) receptor agonist

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Weeks 25-52+: Maintenance and continued slow progress

In February 2026, researchers concluded that weight loss drugs containing tirzepatide may help lower the risk of eye disease in people with type 2 diabetes.