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Mechanistically, ketogenic metabolic therapy has been proposed to i) enhance mitochondrial biogenesis and energy efficiency, ii) reduce oxidative stress and systemic inflammation, iii) modulate glutamatergic neurotransmission and iv) increase BDNF expression and neuroplasticity

The medication's blood-sugar-lowering effect becomes dangerous primarily when combined with other insulin-promoting drugs, not because semaglutide itself triggers hypoglycemia in isolation

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Cost and Availability This is semaglutide's biggest practical advantage

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