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Available from: [18] Laukkarinen J, Sand J, Aittomki S, Prsti I, Kbi P, Kalliovalkama J, et al

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This includes DNA damage that is leading to mutations and strand breaks, lipid peroxidation of cell membranes (disruption of fluidity and integrity), and denaturation of critical functional proteins, which collectively drive the cell towards apoptosis and contribute to the irreversible loss of beta-cell mass [86]

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