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Third, while GLP-1RAs are well studied in type 2 diabetes, data for primary prevention in non-diabetic but high-risk individuals remain sparse, including patients with prior ischaemic stroke or transient ischaemic attack and those with high vascular risk driven by obesity, metabolic syndrome, or chronic kidney disease

Potential to Impact Current Practice: Increased doses of NAC are likely required to avoid hepatotoxicity in massive acetaminophen overdoses above 300 mcg/mL line or with ingestions above 32 grams

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