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Research shows that 10 pounds of weight loss can lower LDL cholesterol by 5-8 mg/dL on average

Prioritize protein (0.7 to 1.0 grams per pound of target body weight), eat frequent small meals rather than large infrequent ones, limit high-fat foods during dose increases to reduce nausea, stay hydrated, and avoid alcohol (which worsens both GI side effects and calorie intake)

These features may suggest atypical anorexia nervosa

If a dose of a once-weekly GLP-1 medication is missed, patients should follow product-specific guidance

Peptide therapy is not appropriate for every patient

10.1016/j.cmet.2012.03.015 21 HorneR