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Wisdom, G

The proponents of coffee enema use believe that the cafestol palmitate in coffee increases the activity of glutathione S-transferase, an enzyme that cause dilatation of bile ducts and excretion of bile through the colon wall, and that the coffee fluid stimulates peristalsis and drainage of bile from the gut [9,10,13]

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Li X, Frye MA, Shelton RC (2012) Review of pharmacological treatment in mood disorders and future directions for drug development

And if you want to learn why experts believe 5-10 grams is ideal, check out our article on L-glutamine dosage

Removes the colon