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Notably, we recently demonstrated that HITI outperforms HDR in terms of knock-in efficacy for GFP gene at the Alb locus in mouse hepatocyte when using clinically relevant, lipid nanoparticle (LNP)-based deliver systems

It stimulates collagen, dermatan sulfate, chondroitin sulfate, and the small proteoglycan, decorin

Helps maintain energy and muscle function

post-treatment comparisons: To evaluate treatment effects on body composition, five metrics (fat mass, muscle mass, body fat percentage, muscle percentage, and muscle-to-fat ratio) were assessed across six regions (right/left arm, right/left leg, android, gynoid)

doi: 10.1006/bbrc.1997.6697

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