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Originally developed and increasingly used for the treatment of type 2 diabetes, these medications have proven highly effective in promoting weight loss, at least during treatment [3,4,5], sparking widespread public interest
doi: 10.1016/j.canlet.2023.216285 127 LiFSiWXiaLYinDWeiTTaoMet al
The comparator arm was placebo, a GLP-1 RA (subcutaneous administration of semaglutide 1 mg once-weekly) and basal insulin in three [18, 19, 22], one [24, 25] and two trials [20, 21], respectively, while one trial included both a placebo arm and a GLP-1 RA arm (dulaglutide 1.5 mg once-weekly) [23]