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Similar evidence has been obtained in non-diabetic male mice 50 and rats 51

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J Fungi 6:119

Multiply by 100 = 62.5 units

In contrast to traditional antidepressants that predominantly target a singular pathway, herbal supplements may offer more comprehensive neurobiological advantages that correspond with the complex etiology of depressive conditions (49)

If you were to take a 2.4 mg dose only once a month, you would be hitting your system with a massive amount of medication after it has had weeks to reset. This is a recipe for severe gastrointestinal distress