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By modulating neurotransmitter levels, reducing neuroinflammation (40), and enhancing cognitive function through oxidative stress protection and increased hippocampal synaptic plasticity (36), it exerts protective effects against AD, as evidenced in preclinical studies
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8,60 While BBB-permeable Bs in particular are associated with fatigue 33 and subjective changes in sleep, 61 these side effects cannot easily be separated from the impact of Bs on peripheral blood pressure, 62 and objective effects of non-REM sleep in a hypertensive population have not yet been investigated