Clinical trials document headache incidence ranging from 515% depending on the medication, dose, and study population
The trial was stopped early because the independent data monitoring committee determined it would be unethical to continue the placebo arm
Additionally, injectable compounded products, found to contain more or less drug product than the labeled strength or which reconstitute at a different rate than intended, may result in either too much or too little medication being administered
On the physiological level, these improvements come with lower fasting insulin, C-peptide, and HOMA2-IR, which are all indicators of enhanced insulin sensitivity
Alzheimers & dementia: the journal of the Alzheimers Association 7 , 280292, (2011)
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