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While these trials used different populations and durations, the magnitude difference has driven clinicians to consider tirzepatide when patients plateau on semaglutide

Brand-name semaglutide (Ozempic, Wegovy, Rybelsus) is manufactured by Novo Nordisk under strict FDA oversight

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A Novo Nordisk spokesperson cited limitations of the study that might skew the results, including a failure to fully consider patients' risk factors for gastrointestinal disorders

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