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The weight-loss results continued to the 48-week endpoint, with the 12 mg (highest dose) retatrutide group achieving an average body weight reduction of 24.2%, while the placebo group only saw a 2.1% change

This step is especially important if you have existing health conditions or are on medication

Many mainstream advocates apply the drug treatment without lifestyle and eating behaviour support, so that the drugs become deemed, life-long

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It works by reducing melanin overproduction caused by sun damage, pollution, and aging, revealing a clearer, more even complexion

For a deeper look at how the estrobolome shapes your hormonal health, read our guide to the guthormone connection in perimenopause