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Interestingly, MYTHO has been reported to be fused in frame with ABCC6 and ARL16 genes in acute myeloid leukemia and lung squamous cell carcinoma, but the pathogenetic role of the fused transcripts has not yet been explored (39)
Overall death rates among hospitalized patients range between 5 and 15%, with greater rates seen in ICUs
This lactate-ABCF1 (K430la)-HIF1A-lactate loop is mediated by lactylation and histone methylation
E.Sanchez-MartinezA.Delgado-CamprubiM.IvattR
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