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Conversely, autophagy appears to protect against apoptotic cell death by regulating proteins involved in both pathways, including Bcl-2 and Bcl-xL, and Beclin1 (Pattingre et al., 2005

To make matters worse, chronic diseases (e.g., type 2 diabetes and heart disease ) can deplete GSH levels, making bodily cells more prone to oxidative stress, or cell damage ( 1 , 2 , 7 )

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